Bremelanotide (PT-141) 10 mg/mL – 5 mL Vial Overview
Concentration: 10 mg/mL
Total per vial: 50 mg
Route: Subcutaneous injection (usually belly or thigh)
Class: Melanocortin receptor agonist (acts on MC-4R)
Key Benefits (Men & Women)
For Women:
Increases sexual desire and arousal
Improves lubrication and pleasure
Helps with low libido (HSDD) without affecting hormones
May benefit menopausal or perimenopausal women
For Men:
Improves erectile response (even without low testosterone)
Enhances sexual excitement and pleasure
Works independently of nitric oxide, so great for men who don’t respond to PDE5 inhibitors (Viagra, Cialis)
Boosts spontaneous desire (libido)
⚠️ Common Side Effects
| Side Effect | Frequency |
|---|---|
| Nausea | Moderate (esp. at higher doses) |
| Flushing (face/warmth) | Mild to moderate |
| Headache | Occasional |
| Increased BP/heart rate | Rare, transient |
| Injection site redness | Rare |
Tip: Taking with food or reducing the dose can lower nausea.
Typical Dosage Guidelines
For Men:
Dose: 1.0 mg to 2.0 mg
Volume: 0.10 mL to 0.20 mL (based on 10 mg/mL concentration)
Timing: Inject 30–60 minutes before sexual activity
Max Frequency: 2–3 times per week
Onset: Within 30–45 minutes
Duration: 4–6 hours of heightened arousal/performance
For Women:
Dose: 0.75 mg to 1.25 mg
Volume: 0.075 mL to 0.125 mL
Timing: Inject 45–60 minutes before intimacy
Max Frequency: 2x per week
Notes: Start low (0.75 mg) to minimize side effects
Sample Use Plan from a 2 mL Vial (20 mg total):
| Dose | Volume (mL) | # of Doses in Vial |
|---|---|---|
| 1.0 mg | 0.10 mL | 50 doses |
| 2.0 mg | 0.20 mL | 25 doses |
Ideal Candidates
Men with performance anxiety, erectile dysfunction, or loss of excitement
Women with low libido, especially not due to hormonal causes
Couples looking to enhance intimacy naturally